Lucullus
NEXT WEBINAR: LUCULLUS® AS THE CONTROL SOFTWARE IN A NOVEL METHOD FOR ANAEROBIC SINGLE-CELL PROTEIN PRODUCTION
April 10, 2024Learn how Lucullus® is used as a control software at the Norwegian University of Life Sciences (NMBU) to develop a novel method for single-cell protein production.
AUTOMATED EVOLUTIONARY ENGINEERING OF MICROORGANISMS IN BIOREACTOR SYSTEMS USING THE SOFTWARE LUCULLUS®
March 14, 2024The article explores how automating evolutionary engineering with the Lucullus® system can significantly enhance the efficiency of bioethanol production.
ADVANCED BIOPROCESS MONITORING AND CONTROL VIA THE LUCULLUS® REST API INTERFACE
February 28, 2024The Lucullus® REST API interface meets the requirements to offer a seamless data exchange capability within a local network or over the Internet.
FULLY AUTOMATED KLA DETERMINATION WITH LUCULLUS®
February 22, 2024Learn how to get a grip on oxygen transfer in bioreactors with fully automated kLa determination using Lucullus® Software.
LUCULLUS® RELEASE NOTES VERSION 24.1.0
January 25, 2024Securecell AG has released a new version of Lucullus®. The latest update follows version 23.0.0 and is named version 24.1.0 based on the new version naming convention.
GETTING A GRIP ON OXYGEN TRANSFER IN BIOREACTORS: AUTOMATED kLa DETERMINATION USING THE SOFTWARE LUCULLUS®
January 8, 2024This application note outlines a fully automated method to determine the kLa parameter based on the static gassing-out method, using the software Lucullus® and Getinge Applikon bioreactor systems.
ADVANCED PROCESS CONTROL VIA THE LUCULLUS REST API
October 19, 2023Learn how ZHAW (School of Life Sciences and Facility Management) highlights applications of the Lucullus REST API with Python.
LUCULLUS® AS CENTRAL PROCESS CONTROL SOFTWARE IN GMP PRODUCTION OF MONOCLONAL ANTIBODIES
June 28, 2023In this success story, we provide an overview of the application of our products at one of our major customers from process development to GMP production using the example of a mAb process .
LUCULLUS® RELEASE NOTES VERSION 23
April 13, 2023Securecell has released a new version of Lucullus®. The latest update comes with many new features such as UTF-8, Windows 11 and new Linux OS Support.
DIGITALIZATION AND STATE-OF-ROUTINE BIOPROCESS MONITORING AND CONTROL
March 21, 2023This article introduces the Lucullus® installation at Teva and highlights the workflow improvements through centralized process and data management.
VACCINE MANUFACTURING USING ICELLIS® REACTOR SYSTEMS IS ORCHESTRATED BY LUCULLUS® IN A VALIDATED ENVIRONMENT AT IDT BIOLOGIKA
October 9, 2022The demand for vaccines, cell and gene therapeutics, and generally biologic manufacturing has continuously increased over the past decade.
SEAMLESS CANDIDATE ANTIMICROBIAL AGENT PRODUCTION AT THE HZI BRAUNSCHWEIG SUPPORTED BY LUCULLUS®
September 27, 2022In the “microbial drugs” department at the Helmholtz Center for Infection Research (HZI) in Braunschweig Germany, a high-tech laboratory environment was built embracing the bioprocessing 4.0 cornerstones.
CELEBRATING EIGHT YEARS OF SECURECELL AG AND GETINGE APPLIKON COLLABORATION
August 30, 2022Together, the two companies look back at eight years of joint success having provided bioprocess solutions to hundreds of customers worldwide.
LUCULLUS® MEDIA KITCHEN - DIGITALLY TAILORED MEDIA PREPARATION
August 25, 2022Bioprocessing 4.0, the biopharmaceutical version of Industry 4.0, is defined as the digital transformation and automation of biopharmaceutical processes with the aim to drive manufacturing ...
NEW PARTNERSHIP WITH DATAHOW AG
July 9, 2022Securecell AG and DataHow AG announce their partnership with the goal to accelerate bioprocess development through harmonized data integration, overarching process automation, and machine learning-based models.
LEVERAGING SOFTWARE INNOVATIONS FOR AUTOMATED DEVELOPMENT AND OPTIMIZATION OF MAMMALIAN CELL CULTURE BIOPROCESSES
May 16, 2022Bioprocess laboratories with multiple lab-scale bioreactors often execute cultivation experiments in parallel with varying process parameters for process development and optimization purposes.
LUCULLUS EMPOWERS OVER 100 BIOREACTORS AT AMYRIS
April 12, 2022In 2021 Securecell engaged with Amyris, a biotechnology company headquartered in Emeryville, California and publicly traded under $AMRS on Nasdaq.
RELEASE NOTES LUCULLUS VERSION 3.11
April 4, 2022Securecell AG has released a new version of Lucullus PIMS. This latest update called version 3.11 comes with many new features, focusing on a faster and easier user experience, with many functions brought to a higher level, ...
LUCULLUS®: VALIDATED DATA HISTORIAN FOR MRNA VACCINE PRODUCTION PROCESSES
February 10, 2022Vaccines based on messenger RNA (mRNA) gained awareness during the COVID-19 pandemic. This novel alternative to conventional vaccines is emerging for several reasons: on the one hand, mRNA vaccines only ...
BIOPROCESSING 4.0 DEMANDS (AND REWARDS) FINE-TUNED COORDINATION
March 2, 2021Bioprocessing 4.0 is all about digitalization and how it can streamline the analysis and multidirectional communication of data—be it between equipment, among unit operations, or across groups and stages of development.
NEXT GENERATION MEAT
December 2, 2020The world population is expected to reach 9.6 billion people by 2050, the middle class is growing, and meat consumption is expected to increase by 70%. Meat production requires a great amount of resources: 34 kgs of feed are necessary to produce 1 kg of meat, the same kg of meat requires ca..
PAT SOLUTIONS FOR THE FUTURE OF BIOPROCESSING 4.0
November 26, 2020Pharmaceuticals have a prominent role in healthcare and their manufacturing requires innovative tools, scientific and engineering knowledge, and must at the same time comply with strict regulations.
AUTOMATION INCREASES PRODUCTIVITY IN BIOPROCESS DEVELOPMENT
October 14, 2020The design space of bioprocesses strongly depends on the technological limits of a system. Digitalization helps to push these boundaries and reach new optimization. A vivid example of this technical extension is the use of additional PAT tools to monitor and control bioprocesses.
INTELLIGENT & INTEGRATED BIOPROCESSING LAB
September 16, 2020Securecell, ZHAW, and Innosuisse are collaborating to generate an intelligent and integrated bioprocessing lab (i2BPLab) where the applicability of Lucullus® and Numera® will be expanded on top of their features to precultures, media preparation, warehousing, and detailed monitoring of bioprocess physiology.
EMPOWERING BIOPHARMA FOR FULL BIOPROCESS DEVELOPMENT AUTOMATION
August 19, 2020Securecell offers a complete automated 24/7 device for sampling and sample processing to “close the loop” between analytics and process units. Discover in this GEN tech article how Numera® can dramatically implement productivity in biopharma process development.
THE HIGH-TECH SECRET BEHIND THE TRADITIONAL CHEESE SWISSNESS
July 2, 2020Cheese is Switzerland’s most important agricultural-export product: around 170’000 tons of cheese are produced per year (40% of the total Swiss milk amount) with a value of around CHF 600 million. Agroscope, a federal research institute in Liebefeld, near Bern, Switzerland ....
BIOPROCESS INFORMATION MANAGEMENT WITH LUCULLUS PIMS FOR BIOCHEMICAL ENGINEERING AT TU WIEN
April 3, 2020At Technische Universität Wien an innovative laboratory develops and optimizes a wide variety of bioprocesses; those operations require multiple bioreactors and equipment and produce an incredible amount of data.
LUCULLUS PIMS FOR EVENT-BASED PROCESS CONTROL
October 9, 2019Process control is a central task in bioprocess development and production. Apart from common control tasks including pH, temperature or dissolved oxygen, more advanced control tasks must be mastered.
ON-LINE HPLC ANALYSIS AND DATA INTEGRATION WITH NUMERA AND LUCULLUS PIMS SHOWN ON THE EXAMPLE OF A CHO PROCESS
April 9, 2019HPLC is the common reference method for product and metabolite analysis in bio-processes. Sampling is needed for these analyses, resulting in off-line measure-ments along the process.
NUMERA & LUCULLUS – AN INTEGRATED PAT SOLUTION COMBINING AUTOMATED SAMPLING AND PROCESS CONTROL
April 9, 2019This application note presents two unique PAT tools, which can be used separately or together as an integrated PAT solution. The Numera system enables automated sampling, sample preparation, ...
GLUCOSE MONITORING AND CONTROL USING NUMERA, LUCULLUS PIMS AND CEDEX® BIO HT ANALYZER
April 9, 2019Critical process parameters (CPPs) such as glucose must be monitored and con-trolled in every bioprocess in order to reach the desired product quality in the most efficient way.