Learn how ZHAW (School of Life Sciences and Facility Management) highlights applications of the Lucullus REST API with Python.
In this success story, we provide an overview of the application of our products at one of our major customers from process development to GMP production using the example of a mAb process .
This article introduces the Lucullus® installation at Teva and highlights the workflow improvements through centralized process and data management.
The demand for vaccines, cell and gene therapeutics, and generally biologic manufacturing has continuously increased over the past decade.
In the “microbial drugs” department at the Helmholtz Center for Infection Research (HZI) in Braunschweig Germany, a high-tech laboratory environment was built embracing the bioprocessing 4.0 cornerstones.
Together, the two companies look back at eight years of joint success having provided bioprocess solutions to hundreds of customers worldwide.
Bioprocessing 4.0, the biopharmaceutical version of Industry 4.0, is defined as the digital transformation and automation of biopharmaceutical processes with the aim to drive manufacturing ...
Securecell AG and DataHow AG announce their partnership with the goal to accelerate bioprocess development through harmonized data integration, overarching process automation, and machine learning-based models.
Bioprocess laboratories with multiple lab-scale bioreactors often execute cultivation experiments in parallel with varying process parameters for process development and optimization purposes.
Securecell AG has released a new version of Lucullus PIMS. This latest update called version 3.11 comes with many new features, focusing on a faster and easier user experience, with many functions brought to a higher level, ...
Vaccines based on messenger RNA (mRNA) gained awareness during the COVID-19 pandemic. This novel alternative to conventional vaccines is emerging for several reasons: on the one hand, mRNA vaccines only ...
Bioprocessing 4.0 is all about digitalization and how it can streamline the analysis and multidirectional communication of data—be it between equipment, among unit operations, or across groups and stages of development.
The world population is expected to reach 9.6 billion people by 2050, the middle class is growing, and meat consumption is expected to increase by 70%. Meat production requires a great amount of resources: 34 kgs of feed are necessary to produce 1 kg of meat, the same kg of meat requires ca..
Pharmaceuticals have a prominent role in healthcare and their manufacturing requires innovative tools, scientific and engineering knowledge, and must at the same time comply with strict regulations.
The design space of bioprocesses strongly depends on the technological limits of a system. Digitalization helps to push these boundaries and reach new optimization. A vivid example of this technical extension is the use of additional PAT tools to monitor and control bioprocesses.
Securecell, ZHAW, and Innosuisse are collaborating to generate an intelligent and integrated bioprocessing lab (i2BPLab) where the applicability of Lucullus® and Numera® will be expanded on top of their features to precultures, media preparation, warehousing, and detailed monitoring of bioprocess physiology.
Securecell offers a complete automated 24/7 device for sampling and sample processing to “close the loop” between analytics and process units. Discover in this GEN tech article how Numera® can dramatically implement productivity in biopharma process development.
Cheese is Switzerland’s most important agricultural-export product: around 170’000 tons of cheese are produced per year (40% of the total Swiss milk amount) with a value of around CHF 600 million. Agroscope, a federal research institute in Liebefeld, near Bern, Switzerland ....
At Technische Universität Wien an innovative laboratory develops and optimizes a wide variety of bioprocesses; those operations require multiple bioreactors and equipment and produce an incredible amount of data.
Process control is a central task in bioprocess development and production. Apart from common control tasks including pH, temperature or dissolved oxygen, more advanced control tasks must be mastered.
HPLC is the common reference method for product and metabolite analysis in bio-processes. Sampling is needed for these analyses, resulting in off-line measure-ments along the process.
This application note presents two unique PAT tools, which can be used separately or together as an integrated PAT solution. The Numera system enables automated sampling, sample preparation, ...
Critical process parameters (CPPs) such as glucose must be monitored and con-trolled in every bioprocess in order to reach the desired product quality in the most efficient way.
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