

NUMERA 3 is an advanced automated sampling and online analytics system that optimizes labs with daily, consistent sample automation. With capabilities to dilute, filter, and cold store samples, Numera 3’s efficiency output can reduce lab labor by up to 62%.


Numera 3 provides seamless integration to your lab automation with simpler tube management, a larger touchscreen, and refreshed UI. Whether you’re working with single-use bench-top reactors or scaling up to production, Numera 3 adapts to your needs.
Its modular design supports everything from single reactor sampling and storage to complex multi-reactor setups with automated sample preparation and direct integration of on-line analyzers. Paired with a variety of analytical instruments, Numera 3 enables precise, real-time data collection without manual intervention.
When combined with the Lucullus® Software, Numera 3 orchestrates your entire workflow – from sampling and measurement to process monitoring and control – giving you the tools to optimize efficiency, consistency, and quality at every step.

Numera 3, what’s new
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- Enhanced User Experience – Larger display and more intuitive operation for smoother workflows and greater flexibility.
- Effortless Installation – Universal Sampling Sets simplify setup, reduce complexity, and cut down on inventory.
- Greater Connectivity – Now supports up to 6 analyzers (previously 4) in parallel for expanded process insights.
- Advanced Sample Processing – Extended dilution range up to 1:100 and optimized filtration for high-density CHO cultures (up to 20 million cells/mL).
- Lucullus® UI Integration – Advanced control and monitoring directly within the Lucullus® interface.
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Choose your configuration
Sample Collection and Storage
Automatically collect samples from connected bioreactors and preserve them at 4–8°C to ensure sample integrity for subsequent analysis.

Automated Sample Processing
Automate sample processing with precise dilution (up to 1:100) and advanced filtration, enabling reliable collection of cell-free samples.

Integrated Online Analytics
Achieve real-time insights through automated, parallel analysis of your samples with integrated cell counters, biochemical analyzers, and HPLC systems.

High-Density Sample Processing
Complete your setup with the centrifugation module, delivering cell-free samples from high-density cultures—optimally prepared for LC-MS analysis.
Still looking for a reason to bring Numera 3 to your lab?


Automated pathway to online CQA for high density samples
This is a revolutionary concept. Numera 3 will add an integrated centrifugation unit (CFU) to its automation ecosphere, capable of processing high-density samples up to 150 million cells per mL.
The CFU will provide a groundbreaking workflow, automating liquid chromatography and critical quality applications online, without human intervention.

