NEXT WEBINAR: DIGITAL BIOREACTORS FOR FAST AND PREDICTABLE SCALING OF SHEAR-SENSITIVE CELL CULTURES

What You Will Learn

During the webinar, Ramon will discuss:

• Why conventional scale-up criteria fall short for shear-sensitive cultures
• How a Digital Bioreactor is built and validated experimentally
• How in-silico screening helps find optimal operating conditions across scales
  
  

  Scaling up bioreactors for shear-sensitive cell cultures is time-consuming and costly. As bioreactor volume increases, achieving sufficient mixing and mass transfer without exceeding shear stress limits becomes increasingly difficult. This is particularly important for processes involving shear-sensitive cells growing on microcarriers or as aggregates (spheroids and embryoid bodies). Examples include processes using induced pluripotent stem cells (iPSCs; cell therapy), mesenchymal stem cells (MSCs, cell therapy), Vero cells (vaccines), and even bovine satellite cells (cultivated meat).
  
  

Speakers

Join our panelists for a discussion and Q&A

Collaboration with: